Vitamin K is a fat-soluble vitamin with multiple functions in the body. It is required for normal development, growth and maintenance of the skeleton throughout life. Vitamin K supports the number and activity of osteoclast cells which break down bone tissue, an ongoing process of skeletal maintenance called bone remodeling.
Bone remodeling is a natural way the body removes old or weakened bone tissue in order to make room for new, stronger tissue.* This process is critical to fracture repair and retaining bone density.* Vitamin A also plays a role in stimulating osteoblasts (bone-building cells) to secrete proteins that are required for bone mineralization, including the K2 dependent protein called osteocalcin. Combined, Vitamins A and D support osteocalcin output and the regulation of osteoclasts (bone breakdown cells) and osteoblasts (bone-building cells).*
Vitamin D3 (cholecalciferol) is a fat-soluble vitamin that is essential for maintaining normal calcium metabolism. It supports calcium absorption in the gut and helps maintain adequate serum calcium and phosphate concentrations to enable normal mineralization of bone.
Vitamin D3 is also needed for proper bone growth and bone remodeling by osteoblasts and osteoclasts. Without sufficient Vitamin D, bones can become thin, brittle, or misshapen. Research shows that K2 partners with Vitamin D3 to inhibit the production of osteoclast cells (cells that break down bone) in order to help bone-building osteoblasts catch up to maintain a healthy balance.
Vitamin D3 also supports cardiovascular function and blood pressure within normal ranges. It impacts heart health by supporting the body’s natural cytokine production and vascular function.
Vitamin K2, known as menaquinone (VitaMK-7®), is the form that supports normal bone formation. It is responsible for specific bone proteins that play a regulatory role in bone metabolism. For example, Vitamin K is required for the activation of osteocalcin, a Vitamin K dependant protein that transports calcium from the blood to the bone matrix. When Vitamin K2 is deficient, bone structure and function can be compromised.
Vitamin K2 also has a regulatory effect on Vitamins A and D with regard to osteoclast and osteoblast activity. Factors that cause a Vitamin K deficiency include poor diet and the use of certain prescription drugs, and well as long term actibiotics. The benefit of Vitamin K2 versus K1 is that it works primarily outside of the liver in bones and blood vessels. In blood vessels Vitamin K helps to maintain arterial elasticity.*
Serving Size: 1 capsule
Servings Per Container: 120
Vitamin A (retinyl palmitate) 5000 mcg
Vitamin D3 (cholecalciferol) 125 mcg
Vitamin K2 (MK7®) 500 mcg
Strontium (from strontium citrate) 100 mg
Other Ingredients: Hypromellose, microcrystalline cellulose, vegetable stearate, silica.
Suggested Use: As a dietary supplement, take 1 capsule one time per day, or as directed by your healthcare practitioner.
Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.